Her Royal Highness Princess Senate Mohato Seeiso is the first of two daughters born to His Majesty King Letsie III and Her Majesty Queen 'Masenate Mohato Seeiso.

She was born on 7 October, 2001 at the Maseru Private Hospital. She was christened on November 10, 2001 into the Roman Catholic Church as Mary, at a celebration held the Royal Residence in Matsieng. She attends at Loretta's Pre-school in Maseru.